WASF1 Antibody : FITC
Référence ARP63994_P050-FITC
Conditionnement : 100ul
Marque : Aviva Systems Biology
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WASF1 Antibody (ARP63994_P050)
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| Datasheets/Manuals | Printable datasheet for anti-WASF1 (ARP63994_P050) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish |
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| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | IHC |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the following sequence TPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRP |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 83%; Zebrafish: 92% |
| Peptide Sequence | Synthetic peptide located within the following region: TPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRP |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | Available upon request |
| Gene Symbol | WASF1 |
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| Gene Full Name | WAS protein family, member 1 |
| Alias Symbols | WAVE, SCAR1, WAVE1, NEDALVS |
| NCBI Gene Id | 8936 |
| Protein Name | Wiskott-Aldrich syndrome protein family member 1 |
| Description of Target | The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. |
| Uniprot ID | Q92558 |
| Protein Accession # | NP_003922 |
| Nucleotide Accession # | NM_001024934 |
| Protein Size (# AA) | 559 |
| Molecular Weight | 62 kDa |
| Protein Interactions | IFT20; TRIP10; PRKAR2A; PRKACA; ABL1; ZC3H15; TXNDC9; SORBS2; PTPN12; UBC; RYK; BRK1; SRGAP3; DNMBP; CYFIP2; PSTPIP1; NCKAP1; ACTR2; BAD; ABI1; RAC1; NCK1; NCF1; PFN1; CRK; IL12A; CXCL8; GNAI1; FYN; CDK5; CDC42; GRB2; ACTB; ACTG1; ARPC3; BAIAP2; ARHGEF2; |
