AChRα4 (299)
Katalog-Nummer sc-65862
Size : 200µg/ml
Marke : Santa Cruz Biotechnology
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Anticorps Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 (299): sc-65862
- L'anticorps Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 299 est un monoclonal IgG1 de rat, cité dans 3 publications, fourni en 200 µg/ml
- raised against purified AChR of rat brain origin
- recommandé pour la détection de nicotinic AChRα4 d'origine mouse, rat, human et chicken par WB, IP et IF
- Nous testons actuellement encore nos anticorps secondaires pour trouver la meilleure protéine de liaison pour cet anticorps primaire Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 (299). Veuillez nous contacter si vous avez des questions concernant les réactifs de détection secondaire appropriés.
ACCÈS RAPIDE AUX LIENS
, AChR α 1, AChR α 2, AChR α 3, AChR α 4, AChR α 5, AChR α 6, AChR α 7, AChR α 8 et AChR α 9
Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. AChRα4, also known as EBN, BFNC, EBN1, NACHR, NACRA4, NACHRA4 or CHRNA4, is a 627 amino acid multi-pass membrane protein associated with nocturnal frontal lobe epilepsy type 1 (ENFL1), an autosomal dominant epilepsy characterized by nocturnal seizures with hyperkinetic automatisms and poorly organized stereotyped movements.
| Espèces | Nom du Gène | Gene ID | Localisation chromosomique | Numéro d'accession de l'isoforme (ARNm) | Numéro d'accès aux protéines | Numéro OMIM™ |
|---|---|---|---|---|---|---|
| Human | CHRNA4 | Entrez Gene ID: 1137 | 20q13.33 | XM_011528524, XM_017027624, XM_017027625, NM_000744, NM_001256573 | UniProt ID: P43681 | 600513 |
| Mouse | Chrna4 | Entrez Gene ID: 11438 | 2 H4 | XM_006500551, NM_015730 | UniProt ID: O70174 | N/A |
L'anticorps Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 préféré est l'Anticorps Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 (A-6): sc-74519.
Informations pour la commande
| Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Nicotinic Acetylcholine Receptor alpha 4/CHRNA4 (299) | sc-65862 | 200 µg/ml | .00 |