AGO3 (Protein Argonaute-3, Argonaute3, hAgo3, Eukaryotic Translation Initiation Factor 2C 3, eIF-2C 3, eIF2C 3, EIF2C3) (APC)
Katalog-Nummer 029410-APC-100ul
Size : 100ul
Marke : US Biological
029410-APC Rabbit Anti-AGO3 (Protein Argonaute-3, Argonaute3, hAgo3, Eukaryotic Translation Initiation Factor 2C 3, eIF-2C 3, eIF2C 3, EIF2C3) (APC)
Clone Type
PolyclonalHost
mouseSource
humanSwiss Prot
Q9H9G7Isotype
IgG2a,kGrade
Affinity PurifiedApplications
IC IPCrossreactivity
HuAccession #
NP_079128Shipping Temp
Blue IceStorage Temp
4°C Do Not FreezeEukaryotic translation initiation factor 2C 3, Ago3, belongs to the argonaute family and contains 1 PAZ and 1 Piwi domain. Ago3 is indicated to play a role in the RNA interference (RNAi) pathway, which is important for heterochromatin formation and accurate chromosome segregation. Unlike Ago1 and Ago2, Ago3 and AG04 do not possess the ability to dissociate miRNA duplexes in a minimal in vitro system. Re-introduction of any Ago variant into embyronic (ES) cells deficient for expression of all four Ago variants will rescue miRNA silencing defects and reduce apoptosis.||Applications:|Suitable for use in Immunoprecipitation and Immunocytochemistry. Other applications not tested.||Recommended Dilution:|Immunocytochemistry: 1:500|Optimal dilutions to be determined by the researcher.||Positive Control:|HeLa cells||Storage and Stability:|Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.||Note: Applications are based on unconjugated antibody.