Anti-CD52 (CAMPATH-1) (Mouse) mAb-PE

Katalog-Nummer D204-5

Size : 50Tests

Marke : MBL International

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D204-5
Antibody
50 tests

DATA SHEET

Monoclonal antibody conjugated to PE of 50 tests targeting CAMPATH-1/CD52 for FCM.

TargetCAMPATH-1/CD52
Product TypeAntibody
ApplicationFCM
ClonalityMonoclonal
ConjugatePE
IsotypeIgG2a
ImmunogenTransgenic mouse spleen cell IL-2Ralpha
Host SpeciesRat
Species ReactivityMouse
FormulationPBS/1% BSA/0.09% NaN3
Research AreaImmunology, Cell Biology
Description/BackgroundCAMPATH-1, also known as CD52, is a heavily glycosylated, GPI-anchored protein expressed at high levels on almost all thymocytes, lymphocytes, monocytes, and macrophages. CAMPATH-1 is an exceptionally good target for complement-mediated cell lysis and antibody-mediated cellular cytotoxicity. Humanized CAMPATH-1 antibodies have been used therapeutically to effectively deplete lymphocytes in allogeneic bone marrow transplants, hematologic malignancies, and autoimmune diseases. Clinical trials suggest CAMPATH-1 antibodies are especially promising in the treatment of leukemia, non-Hodgkin lymphomas, and rheumatoid arthritis. The apparent size of CAMPATH-1 by SDS-PAGE is 25-29 kDa; however, the actual molecule is much smaller, ~ 8-9 kDa as confirmed by total structure analysis and mass spectrometry.
Storage Temperature4°C
ProtocolsFCM
Clone NumberBTG-2G
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
D204-5
Antibody
50 tests