General Info
| Host: | Rabbit |
| Applications: | ELISA/IHC/IP/WB |
| Reactivity: | Bovine/Cat/Human/Monkey/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-DEK (324-373) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Purification: | Affinity Purified |
| Concentration: | 0.65 µg/µl |
| Dilution Range: | WB: 1:500-1:750DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:50-1:150 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
Information
| Gene Symbol: | DEK |
| Gene ID: | 7913 |
| Uniprot ID: | DEK_HUMAN |
| Immunogen Region: | 324-373 |
| Immunogen: | Synthetic peptide taken within residues corresponding to a region within amino acids 324-373 of human DEK. |
Description
| Tissue Specificity | Ubiquitous. Expressed at relatively high levels. |
| Post Translational Modifications | Phosphorylated by CK2. Phosphorylation fluctuates during the cell cycle with a moderate peak during G(1) phase, and weakens the binding of DEK to DNA. |
| Function | Involved in chromatin organization. |
| Protein Name | Protein Dek |
| Database Links | Reactome: R-HSA-5250924Reactome: R-HSA-8864260Reactome: R-HSA-9616222 |
| Cellular Localisation | NucleusEnriched In Regions Where Chromatin Is Decondensed Or Sparse In The Interphase Nuclei |
| Alternative Antibody Names | Anti-Protein Dek antibodyAnti-DEK antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance