Reagenzien und Instrumente für die Immunologie Zellbiologie und Molekularbiologie
 
> CD11B (Integrin alpha-M, CD11 Antigen-like Family Member B, CR-3 alpha Chain, Cell Surface Glycoprotein MAC-1 Subunit alpha, Leukocyte Adhesion Receptor MO1, Neutrophil Adherence Receptor, ITGAM, CR3A, MGC117044) (PE)

CD11B (Integrin alpha-M, CD11 Antigen-like Family Member B, CR-3 alpha Chain, Cell Surface Glycoprotein MAC-1 Subunit alpha, Leukocyte Adhesion Receptor MO1, Neutrophil Adherence Receptor, ITGAM, CR3A, MGC117044) (PE)

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Katalog-Nummer C2262-36-PE-100ul

Size : 100ul

Marke : US Biological

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C2262-36-PE CD11B (Integrin alpha-M, CD11 Antigen-like Family Member B, CR-3 alpha Chain, Cell Surface Glycoprotein MAC-1 Subunit alpha, Leukocyte Adhesion Receptor MO1, Neutrophil Adherence Receptor, ITGAM, CR3A, MGC117044) (PE)

Clone Type
Polyclonal
Host
mouse
Source
human
Swiss Prot
P11215
Isotype
IgG1,k
Grade
Purified
Applications
FC IHC
Crossreactivity
Hu Mk Po
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze

Integrin alpha M (ITGAM) is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 ( alphaMBeta2) molecule, also known as macrophage-1 antigen (Mac-1) or complement receptor 3 (CR3). ITGAM is also known as CR3A, and cluster of differentiation molecule 11B (CD11B).||Applications:|Suitable for use in Immunohistochemistry, Flow Cytometry and Blocking Studies. Other applications not tested. ||Recommended Dilution:|Immunohistochemistry: frozen|Optimal dilutions to be determined by the researcher.||Storage and Stability:|Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.||Note: Applications are based on unconjugated antibody.

Applications
Product Type: Mab|Isotype: IgG1,k|Clone No: ICRF44|Host: mouse|Source: human|Concentration: As reported|Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).|Purity: Purified|Immunogen: Rheumatoid synovial cells and human monocytes|Specificity: Recognizes human CD11b. Species Crossreactivity: Porcine, Rhesus. Cynomolgus, Chimpanzee and Baboon||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Rheumatoid synovial cells and human monocytes
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity
Purified
Specificity
Recognizes human CD11b. Species Crossreactivity: Porcine, Rhesus. Cynomolgus, Chimpanzee and Baboon
References
1. McMichael, A.K., P.C.L. Beverly, S. Cobbold, M.J. Crumpton, W. Gilks, F.M. Gotch, N. Hogg, M. Horton, N. Ling, I.C.M. MacLennan, D.Y. Mason, C. Milstein, D. Spiegelhalter, and H. Waldmann, eds. 1987. Leukocyte Typing III: White Cell Differentiation Antigens, Oxford University Press, Oxford.|2. Knapp, W., B. Dorken, W.R. GIlks, E.P. Rieber, R.E. Schmidt, H. Stein, A.E.G.K. Von dem Borne, eds. 1989. Leukocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, Oxford.|3. Springer, T.A. 1994. Cell 76:301.|4. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD11b Section, Academic Press, New York, p. 158.|5. Lee, J.O., L.A. Bankston, M.A. Arnaout, and R.C. Liddington. 1995. Structure 3:1333.|6. Zhang, L.., and E.F. Plow. 1996. J. Biol. Chem. 271:18211.|7. Davis, G.E. 1992. Exp. Cell. Res. 200:242.|8. Perry, H.R., and R.F. Todd, III. 1996. Immunol. Today 17:209.