CD44 (CD44, LHR, MDU2, MDU3, MIC4, CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, Phagocytic glycoprotein I, CD_antigen=CD44) (APC)

Katalog-Nummer 030854-APC-200ul

Size : 200ul

Marke : US Biological

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030854-APC CD44 (CD44, LHR, MDU2, MDU3, MIC4, CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, Phagocytic glycoprotein I, CD_antigen=CD44) (APC) discontinued

Clone Type
Polyclonal
Host
mouse
Source
human
Swiss Prot
P16070
Isotype
IgG2a,k
Grade
Affinity Purified
Applications
FLISA IF IHC WB
Crossreactivity
Hu
Accession #
NP_000601.3
Gene #
CD44
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.||Applications:|Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry (Not Tested), FLISA.||Recommended Dilution:|Optimal dilutions to be determined by the researcher. ||Storage and Stability:|May be stored at 4°C for short-term only. For long-term storage, store at -20°C with glycerol. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Do not freeze APC conjugates. Light sensitive.||Note: Applications are based on unconjugated antibody.

Applications
Product Type: Mab|Isotype: IgG2a,k|Clone No: Hermes-3|Host: mouse|Source: human|Concentration: As Reported|Form: Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).|Purity: Purified by Protein G affinity chromatography.|Immunogen: Recombinant protein corresponding to human CD44 (P16070)|Specificity: Recognizes human CD44.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Recombinant protein corresponding to human CD44 (P16070)
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Purity
Purified by Protein G affinity chromatography.
Specificity
Recognizes human CD44.
References
1. Cunha, C.B., et al. Lab. Invest. 90(11):1604-1614(2010). 2. Somasunderam, A., et al. Biochemistry 49(42):9106-9112(2010. 3. Wolny, P.M., et al. J. Biol. Chem. 285(39):30170-30180(2010). 4. Ryckman, K.K., et al. PLoS ONE 5 (8), E12273 (2010). 5. Scartozzi, M., et al. Anal. Quant. Cytol. Histol. 31(6):417-423(2009)