GPER1 Antibody (OABF00668-100UL) : HRP
Katalog-Nummer OABF00668-HRP
Size : 100ul
Marke : Aviva Systems Biology
Contact local distributor :
Telefonnummer : +1 850 650 7790
| Datasheets/Manuals | Printable datasheet for GPER1 Antibody (OABF00668) |
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| Tested Species Reactivity | Human, Mouse, Rat |
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| Predicted Species Reactivity | Bovine|Chicken|Horse|Human|Mouse|Rabbit|Rat |
| Product Format | Liquid Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Host | Rabbit |
| Conjugation | Unconjugated |
| Application | ELISA, FC, ICC, IF, IHC-Fr, IHC-P, WB |
| Reconstitution and Storage | -20°C |
| Immunogen | KLH conjugated synthetic peptide derived from human GPR30 |
| Purification | Protein A Purified |
| Concentration | 1 ug/ul |
| Application Info | WB: 1:300~1000 ELISA: 1:500~1000 FC: 1:20~100 IHC-P: 1:200~400 IHC-F: 1:100~500 Fluorescent (IHC-P): 1:50~200 Fluorescent (IHC-F): 1:50~200 Fluorescent-ICC: 1:50~200 |
| Gene Symbol | GPER1 |
|---|---|
| Gene Full Name | G protein-coupled estrogen receptor 1 |
| Alias Symbols | CEPR;chemoattractant receptor-like 2;chemokine receptor-like 2;CMKRL2;constitutively expressed peptide-like receptor;DRY12;FEG-1;flow-induced endothelial G-protein coupled receptor 1;G protein-coupled estrogen receptor 1;G protein-coupled receptor 30;GPCR-Br;GPER;GPR30;G-protein coupled estrogen receptor 1;G-protein coupled receptor 30;heptahelix receptor;IL8-related receptor DRY12;LERGU;LERGU2;LyGPR;lymphocyte-derived G-protein coupled receptor;membrane estrogen receptor;mER. |
| NCBI Gene Id | 2852 |
| Protein Name | G-protein coupled estrogen receptor 1 |
| Description of Target | G-protein coupled estrogen receptor that binds to 17-beta-estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium mobilization and tyrosine kinase Src inducing the release of heparin-bound epidermal growth factor (HB-EGF) and subsequent transactivation of the epidermal growth factor receptor (EGFR), activating downstream signaling pathways such as PI3K/Akt and ERK/MAPK. Mediates pleiotropic functions among others in the cardiovascular, endocrine, reproductive, immune and central nervous systems. Has a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a RAMP3-dependent manner. Regulates arterial blood pressure by stimulating vasodilation and reducing vascular smooth muscle and microvascular endothelial cell proliferation. Plays a role in blood glucose homeostasis contributing to the insulin secretion response by pancreatic beta cells. Triggers mitochondrial apoptosis during pachytene spermatocyte differentiation. Stimulates uterine epithelial cell proliferation. Enhances uterine contractility in response to oxytocin. Contributes to thymic atrophy by inducing apoptosis. Attenuates TNF-mediated endothelial expression of leukocyte adhesion molecules. Promotes neuritogenesis in developing hippocampal neurons. Plays a role in acute neuroprotection against NMDA-induced excitotoxic neuronal death. Increases firing activity and intracellular calcium oscillations in luteinizing hormone-releasing hormone (LHRH) neurons. Inhibits early osteoblast proliferation at growth plate during skeletal development. Inhibits mature adipocyte differentiation and lipid accumulation. Involved in the recruitment of beta-arrestin 2 ARRB2 at the plasma membrane in epithelial cells. Functions also as a receptor for aldosterone mediating rapid regulation of vascular contractibility through the PI3K/ERK signaling pathway. Involved in cancer progression regulation. Stimulates cancer-associated fibroblast (CAF) proliferation by a rapid genomic response through the EGFR/ERK transduction pathway. Associated with EGFR, may act as a transcription factor activating growth regulatory genes (c-fos, cyclin D1). Promotes integrin alpha-5/beta-1 and fibronectin (FN) matrix assembly in breast cancer cells. |
| Uniprot ID | Q99527 |
| Molecular Weight | 42 kDa |
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What is the species homology for "GPER1 Antibody (OABF00668)"?
The tested species reactivity for this item is "Human, Mouse, Rat". This antibody is predicted to have homology to "Bovine|Chicken|Horse|Human|Mouse|Rabbit|Rat".
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How long will it take to receive "GPER1 Antibody (OABF00668)"?
This item is available "3 to 5 business days.".
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What buffer format is "GPER1 Antibody (OABF00668)" provided in?
This item is provided in "Liquid Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.".
Additional format options may be available. For more information please contact info@avivasysbio.com. -
What are other names for "GPER1 Antibody (OABF00668)"?
This target may also be called "CEPR;chemoattractant receptor-like 2;chemokine receptor-like 2;CMKRL2;constitutively expressed peptide-like receptor;DRY12;FEG-1;flow-induced endothelial G-protein coupled receptor 1;G protein-coupled estrogen receptor 1;G protein-coupled receptor 30;GPCR-Br;GPER;GPR30;G-protein coupled estrogen receptor 1;G-protein coupled receptor 30;heptahelix receptor;IL8-related receptor DRY12;LERGU;LERGU2;LyGPR;lymphocyte-derived G-protein coupled receptor;membrane estrogen receptor;mER." in publications.
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What is the shipping cost for "GPER1 Antibody (OABF00668)"?
The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.
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What is the guarantee for "GPER1 Antibody (OABF00668)"?
All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.
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Can I get bulk pricing for "GPER1 Antibody (OABF00668)"?
You can get bulk pricing for this item by going here.
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What is the molecular weight of the protein?
The molecular weight reported by Uniprot for this item is "42 kDa".
Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics. -
What protocols are available for "GPER1 Antibody (OABF00668)"?
We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.
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What are positive controls for "GPER1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What are negative controls for "GPER1"?
We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.
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What other proteins interact with "GPER1"?
This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.
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What biological processes are associated with "GPER1"?
This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.
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What cellular components are associated with "GPER1"?
This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.
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What protein functions are associated with "GPER1"?
This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.