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> GRM1 Antibody (OABF00837-100UL) : FITC

GRM1 Antibody (OABF00837-100UL) : FITC

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Katalog-Nummer OABF00837-FITC

Size : 100ul

Marke : Aviva Systems Biology

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Datasheets/ManualsPrintable datasheet for GRM1 Antibody (OABF00837)
Product Info
Tested Species ReactivityHuman, Mouse, Rat
Predicted Species ReactivityBovine|Chicken|Dog|Horse|Human|Mouse|Porcine|Rat
Product FormatLiquid Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
ClonalityPolyclonal
IsotypeIgG
HostRabbit
ConjugationUnconjugated
ApplicationELISA, FC, ICC, IF, IHC-Fr, IHC-P, WB
Reconstitution and Storage-20°C
ImmunogenKLH conjugated synthetic peptide derived from human GRM1
PurificationProtein A Purified
Concentration1 ug/ul
Application InfoWB: 1:300~1000
ELISA: 1:500~1000
FC: 1:20~100
IHC-P: 1:200~400
IHC-F: 100~500
Fluorescent (IHC-P): 1:50~200
Fluorescent (IHC-F): 1:50~200
Fluorescent-ICC: 1:50~200
ICC: 1:100~500
Gene SymbolGRM1|GRM5
Gene Full Nameglutamate metabotropic receptor 1|glutamate metabotropic receptor 5
Alias Symbolsglutamate receptor, metabotropic 1;glutamate receptor, metabotropic 5;GPRC1A;GPRC1E;metabotropic glutamate receptor 1;metabotropic glutamate receptor 5;MGLU1;mGlu5;MGLUR1;MGLUR5;PPP1R85;PPP1R86;protein phosphatase 1, regulatory subunit 85;protein phosphatase 1, regulatory subunit 86;SCA44;SCAR13.
NCBI Gene Id2911|2915
Description of TargetL-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. The canonical alpha isoform of the metabotropic glutamate receptor 1 gene is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. Alternative splicing results in multiple transcript variants encoding distinct isoforms; some of which may have distinct functions. [provided by RefSeq].

  1. What is the species homology for "GRM1 Antibody (OABF00837)"?

    The tested species reactivity for this item is "Human, Mouse, Rat". This antibody is predicted to have homology to "Bovine|Chicken|Dog|Horse|Human|Mouse|Porcine|Rat".

  2. How long will it take to receive "GRM1 Antibody (OABF00837)"?

    This item is available "3 to 5 business days.".

  3. What buffer format is "GRM1 Antibody (OABF00837)" provided in?

    This item is provided in "Liquid Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "GRM1 Antibody (OABF00837)"?

    This target may also be called "glutamate receptor, metabotropic 1;glutamate receptor, metabotropic 5;GPRC1A;GPRC1E;metabotropic glutamate receptor 1;metabotropic glutamate receptor 5;MGLU1;mGlu5;MGLUR1;MGLUR5;PPP1R85;PPP1R86;protein phosphatase 1, regulatory subunit 85;protein phosphatase 1, regulatory subunit 86;SCA44;SCAR13." in publications.

  5. What is the shipping cost for "GRM1 Antibody (OABF00837)"?

    The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.

  6. What is the guarantee for "GRM1 Antibody (OABF00837)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "GRM1 Antibody (OABF00837)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "GRM1 Antibody (OABF00837)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "GRM1|GRM5"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "GRM1|GRM5"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "GRM1|GRM5"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "GRM1|GRM5"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "GRM1|GRM5"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "GRM1|GRM5"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.