HP1 alpha Monoclonal Antibody, HRP Conjugated
Katalog-Nummer bsm-33377M-HRP
Size : 100ul
Marke : Bioss
Contact local distributor :
Telefonnummer : +1 850 650 7790
HP1 alpha Monoclonal Antibody, HRP Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-33377M-HRP |
| Product Name | HP1 alpha Monoclonal Antibody, HRP Conjugated |
| Applications | WB |
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | HRP |
| Host | Mouse |
| Source | KLH conjugated synthetic peptide derived from human HP1 alpha |
| Clonality | Monoclonal |
| Clone # | 7E3 |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 23468 |
| Swiss Prot | P45973 |
| Synonyms | Antigen p25; HP1-_; CBX5; CBX5_HUMAN; Chromobox homolog 5 (HP1 alpha homolog, Drosophila); Chromobox homolog 5; Chromobox protein homolog 5; Heterochromatin protein 1 alpha; Heterochromatin protein 1; Heterochromatin protein 1 homolog alpha; HP1 alpha; HP1 alpha homolog; HP1; HP1A; HP1Hs alpha. |
| Background | Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
| Application Dilution | |
| WB | 1:300-5000 |