Human Glucose 6 Phosphate Dehydrogenase (G6PD) activation kit by CRISPRa
Katalog-Nummer GA101687
Size : 1kit
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Human Glucose 6 Phosphate Dehydrogenase (G6PD) activation kit by CRISPRa
SKU
GA101687
G6PD CRISPRa kit - CRISPR gene activation of human glucose-6-phosphate dehydrogenase
2 Weeks*
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | G6PD |
| Locus ID | 2539 |
| Components | GA101687G1, Glucose 6 Phosphate Dehydrogenase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101687G2, Glucose 6 Phosphate Dehydrogenase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101687G3, Glucose 6 Phosphate Dehydrogenase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Reference Data | |
| RefSeq | NM_000402, NM_001042351, NM_001360016 |
| UniProt ID | P11413 |
| Synonyms | G6PD1 |
| Summary | This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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| KN201807 | G6PD - human gene knockout kit via CRISPR, HDR mediated | 1 kit | | |
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| KN401807 | G6PD - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit | | |
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.