IL-17A/F (Human) ELISpot Kit

Quantification

Entrez GeneID

Gene Name

IL17A

Gene Alias

CTLA8, IL-17, IL-17A, IL17

Gene Description

interleukin 17A

Omim ID

Gene Ontology

Gene Summary

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq

Other Designations

OTTHUMP00000016597|cytotoxic T-lymphocyte-associated antigen 8|cytotoxic T-lymphocyte-associated protein 8|cytotoxic T-lymphocyte-associated serine esterase 8|interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)

Entrez GeneID

Gene Name

IL17F

Gene Alias

IL-17F, ML-1, ML1

Gene Description

interleukin 17F

Omim ID

Gene Ontology

Gene Summary

The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq

Other Designations

cytokine ML-1