IL7 monoclonal antibody, clone BVD10-11C10 (Biotin)
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- More Files
- Specifications
Product Description
Rat monoclonal antibody raised against recombinant IL7.
Immunogen
Recombinant protein corresponding to human IL7.
Host
Rat
Reactivity
Human
Specificity
human Interleukin-7 (IL-7)1,2. This is a neutralizing antibody.
Form
Liquid
Conjugation
Biotin
Isotype
IgG2a, kappa
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
Enzyme-linked Immunoabsorbent Assay
- Gene Info — IL7
Entrez GeneID
3574Gene Name
IL7
Gene Alias
IL-7
Gene Description
interleukin 7
Omim ID
146660Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. [provided by RefSeq
Other Designations
IL7 nirs variant 6
- Interactomes
- Pathways
- Diseases
- Publication Reference
- Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples.
Abrams JS, Roncarolo MG, Yssel H, Andersson U, Gleich GJ, Silver JE.
Immunological Reviews 1992 Jun; 127:5.
- Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples.