IRS1 (phospho Tyr612) antibody
Katalog-Nummer GTX24868-50ul
Size : 50ul
Marke : GeneTex
Contact local distributor :
Telefonnummer : +1 850 650 7790
1
Host | Rabbit |
|---|---|
Clonality | Polyclonal |
Isotype | IgG |
Application | WB, IHC-P, FACS, IHC |
Reactivity | Human, Mouse, Rat |
| Package | 50 μl |
Datasheet File View product citations for antibody GTX24868 on CiteAb
APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application | Recommended Dilution |
|---|---|
| WB | 1:1000 |
| IHC-P | 1:10-1:100 |
| FACS | 1:20 |
| IHC | Assay dependent |
Not tested in other applications.
Calculated MW
132 kDa. ( Note )
PROPERTIES
Form
Liquid
Buffer
PBS, 0.1% BSA, 50% Glycerol
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human IRS-1 that contains tyrosine 612. The sequence is conserved in mouse, rat and chicken.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
insulin receptor substrate 1 , HIRS-1
Background
This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009]
Database
DATA IMAGES
| | GTX24868 WB ImageWB analysis of samples using GTX24868 IRS1 (phospho Tyr612) antibody. The data show that only the immunogen phosphopeptide blocks the signal, demonstrating the specificity of the antibody. |
| | GTX24868 IHC-P Image IHC-P analysis of human skeletal muscle tissue using GTX24868 IRS1 (phospho Tyr612) antibody. |
Application Reference
Zuliani I et al. Neurotherapeutics 2020; (Epub) The Dysregulation of OGT/OGA Cycle Mediates Tau and APP Neuropathology in Down Syndrome.
Application : WB
Reactivity : Mouse
REVIEW
IRS1 (phospho Tyr612) antibody Cat. No. GTX24868
| Rating | | ( Average 5 based on 1 users reviews) |
| Western Blot(WB) | | ( Average 5 based on 1 users reviews) |
Application Reference
Zuliani I et al. Neurotherapeutics 2020; (Epub) The Dysregulation of OGT/OGA Cycle Mediates Tau and APP Neuropathology in Down Syndrome.
Application : WB
Reactivity : Mouse
| SDS | |
|---|---|
| PBS.pdf | |
| Glycerol.pdf | |
| Sodium Azide.pdf | |
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