Leflunomide-d4
Product Code
TRC-L322752
CAS Number
1189987-23-2
Product Format
Neat
Molecular Formula
C12H5D4F3N2O2
Molecular Weight
274.23
API Family
LeflunomideProduct Type
Stable Isotope Labelled, Metabolite, APIUnlabelled CAS Number
75706-12-6
Documentation
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Product Information
Chemical Data
Analyte Name
Leflunomide-d4
CAS Number
1189987-23-2
Molecular Formula
C12H5D4F3N2O2
Molecular Weight
274.23
SMILES
O=C(NC1=C([2H])C([2H])=C(C(F)(F)F)C([2H])=C1[2H])C2=C(C)ON=C2
Unlabelled CAS Number
75706-12-6
SIL Type
Deuterium
Product Data
Storage Temperature
-20°C
Shipping Temperature
Room Temperature
Country of Origin
CANADA
Product Type
Stable Isotope Labelled; Metabolite; API
Product Format
Neat
API Family
Leflunomide
Product Description
An immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases.This compound is suitable for dihydroorotate dehydrogenase (DHODH) related research.
References: Vrenken, T., et al.: J. Hepatol., 49, 799 (2008),
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