MHC Class I (monomorphic) Mouse Monoclonal Antibody [Clone ID: CVS22]
Katalog-Nummer SM504R
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MHC Class I (monomorphic) Mouse Monoclonal Antibody [Clone ID: CVS22]
SKU
SM504R
MHC Class I (monomorphic) mouse monoclonal antibody, clone CVS22, PE, Purified
| Product Data | |
| Clone Name | CVS22 |
|---|---|
| Application | FC |
| Recommended Dilution | Flow cytometry: Neat, use 10µl to label 10e6 cells in 100µl. |
| Reactivity | Equine |
| Antibody Host | Mouse |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Immunogen | Equine leucocytes |
| Specificity | All tissues |
| Buffer | PBS containing 0.09% Sodium azide, 1% BSA and 5% Sucrose Label: PE State: Purified State: Lyophilised purified IgG Label: R. Phycoerythrin |
| Reconstitution Method | Restore with 1.0 ml distilled water |
| Purification | Affinity chromatography on Protein A |
| Conjugation | PE |
| Storage | Prior to and following reconstitution store the antibody at 2-8°C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
| Stability | Shelf life: one year from despatch. |
| Background | MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. Fibroblasts or neurons however only show a low level of antigen. |
| Synonyms | MHC Class 1, HLA Class 1 |
| Reference Data | |