MRAP, NT (MRAP, C21orf61, FALP, Melanocortin-2 receptor accessory protein, B27, Fat cell-specific low molecular weight protein, Fat tissue-specific low MW protein) (Biotin)

Katalog-Nummer 038576-Biotin-200ul

Size : 200ul

Marke : US Biological

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038576-Biotin MRAP, NT (MRAP, C21orf61, FALP, Melanocortin-2 receptor accessory protein, B27, Fat cell-specific low molecular weight protein, Fat tissue-specific low MW protein) (Biotin) discontinued

Clone Type
Polyclonal
Host
rabbit
Source
human
Swiss Prot
Q8TCY5
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Gene #
MRAP
Shipping Temp
Blue Ice
Storage Temp
-20°C

MRAP encodes a melanocortin receptor-interacting protein. The encoded protein regulates trafficking and function of the melanocortin 2 receptor in the adrenal gland. The encoded protein can also modulate signaling of other melanocortin receptors. Mutations in this gene have been associated with familial glucocorticoid deficiency type 2.||Applications:|Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other potential application, though not tested is Direct Flow Cytometry. Other applications have not been tested. ||Recommended Dilutions:|Immunohistochemistry: Formalin-fixed, paraffin-embedded sections |Optimal dilutions to be determined by the researcher. ||Storage and Stability:|Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.||Note: Applications are based on unconjugated antibody.

Applications
Product Type: Pab|Isotype: IgG|Host: rabbit|Source: human|Concentration: As reported|Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.|Purity: Purified by Protein A and peptide affinity chromatography.|Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 7-36 in the N-terminal region of human MRAP|Specificity: Recognizes human MRAP.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 7-36 in the N-terminal region of human MRAP
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human MRAP.
References
1. Dias, R.P., et al. Eur. J. Endocrinol. 162(2):357-359(2010). 2. Chan, L.F., et al. Proc. Natl. Acad. Sci. U.S.A. 106(15):6146-6151(2009). 3. Webb, T.R., et al. Endocrinology 150(2):720-726(2009)