Obeticholic Acid [459789-99-2]
Katalog-Nummer T1789-10mg
Size : 10mg
Marke : TargetMol
Obeticholic Acid
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Purity:99.97%
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COA HPLC HNMR
Obeticholic Acid
Catalog No. T1789Cas No. 459789-99-2
Obeticholic Acid (6-ECDCA) is a Farnesoid X Receptor Agonist. The mechanism of action of obeticholic acid is as a Farnesoid X Receptor Agonist.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. Pack Size | |
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5 mg | |
10 mg | |
25 mg | |
50 mg | |
100 mg | |
200 mg | |
500 mg | |
1 mL x 10 mM (in DMSO) |
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
Description | Obeticholic Acid (6-ECDCA) is a Farnesoid X Receptor Agonist. The mechanism of action of obeticholic acid is as a Farnesoid X Receptor Agonist. |
Alias | INT-747, 6-Ethylchenodeoxycholic acid, 6-ECDCA |
Molecular Weight | 420.63 |
Formula | C26H44O4 |
Cas No. | 459789-99-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | H2O: < 1 mg/mL (insoluble or slightly soluble) DMSO: 45 mg/mL (106.98 mM) Ethanol: 78 mg/mL (185.4 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg,each
animal weighs 20 g, and the dosage volume is 100 μL. A total of
10 animals were administered, and the formula you used is 5%
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL.
Mother liquor preparation method: 2 mg of drug dissolved in 50 μLDMSO
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μLDMSO
main solution, add 300 μLPEG300
mix well and clarify, then add 50 more μLTween 80, mix well and clarify, then add 600 more μLddH2O
mix well and clarify.
Dose Conversion
You can also refer to dose conversion for different animals. More
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Keywords
AutophagyorallyNR1H4activefarnesoidINT 747FXRObeticholic AcidreceptorInhibitorinhibitINT747