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> p-SCN-Bn-deferoxamine [1222468-90-7]

p-SCN-Bn-deferoxamine [1222468-90-7]

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Katalog-Nummer HY-134797-10mg

Size : 10mg

Marke : MedChemExpress

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p-SCN-Bn-deferoxamine is a linker used to connect antibodies to materials.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

p-SCN-Bn-deferoxamine Chemische Struktur

p-SCN-Bn-deferoxamine Chemische Struktur

CAS. Nr. : 1222468-90-7

This product is a controlled substance and not for sale in your territory.

Based on 1 publication(s) in Google Scholar

Alle Radionuclide-Drug Conjugates (RDCs) Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen
RDC Peptide RDC Antibody RDC Bifunctional Chelator RDC Linker Other
Beschreibung

p-SCN-Bn-deferoxamine is a linker used to connect antibodies to materials[1].

IC50 & Target

RDC Linker

 

Molekulargewicht

752.94

Formel

C33H52N8O8S2
CAS. Nr.

1222468-90-7
Appearance

Solid

Color

White to off-white

SMILES

O=C(CCC(N(CCCCCNC(CCC(N(CCCCCNC(NC1=CC=C(C=C1)N=C=S)=S)O)=O)=O)O)=O)NCCCCCN(C(C)=O)O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : 70 mg/mL (92.97 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3281 mL 6.6406 mL 13.2813 mL
5 mM 0.2656 mL 1.3281 mL 2.6563 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation

Purity: ≥98.0%

COA (250 KB) HNMR (288 KB) MS (71 KB)

Handling Instructions (2659 KB)
Verweise

  • [1]. Sobol NB, et al. ImmunoPET Imaging of Pancreatic Tumors with 89Zr-Labeled Gold Nanoparticle-Antibody Conjugates. Mol Imaging Biol. 2021 Feb;23(1):84-94.  [Content Brief]

  • [1]. Sobol NB, et al. ImmunoPET Imaging of Pancreatic Tumors with 89Zr-Labeled Gold Nanoparticle-Antibody Conjugates. Mol Imaging Biol. 2021 Feb;23(1):84-94.

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3281 mL 6.6406 mL 13.2813 mL 33.2032 mL
5 mM 0.2656 mL 1.3281 mL 2.6563 mL 6.6406 mL
10 mM 0.1328 mL 0.6641 mL 1.3281 mL 3.3203 mL
15 mM 0.0885 mL 0.4427 mL 0.8854 mL 2.2135 mL
20 mM 0.0664 mL 0.3320 mL 0.6641 mL 1.6602 mL
25 mM 0.0531 mL 0.2656 mL 0.5313 mL 1.3281 mL
30 mM 0.0443 mL 0.2214 mL 0.4427 mL 1.1068 mL
40 mM 0.0332 mL 0.1660 mL 0.3320 mL 0.8301 mL
50 mM 0.0266 mL 0.1328 mL 0.2656 mL 0.6641 mL
60 mM 0.0221 mL 0.1107 mL 0.2214 mL 0.5534 mL
80 mM 0.0166 mL 0.0830 mL 0.1660 mL 0.4150 mL
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p-SCN-Bn-deferoxamine Related Classifications

  • Antibody-drug Conjugate/ADC Related
  • Radionuclide-Drug Conjugates (RDCs)
Help & FAQs

Keywords:

p-SCN-Bn-deferoxamine1222468-90-7Radionuclide-Drug Conjugates (RDCs)LinkerInhibitorinhibitorinhibit