PPAR Gamma (ser273) Polyclonal Antibody, APC Conjugated
Katalog-Nummer bs-4888R-APC
Size : 100ul
Marke : Bioss
PPAR Gamma (ser273) Polyclonal Antibody, APC Conjugated
Applications
Reactivity
Predicted Reactivity
Overview | |
Catalog # | bs-4888R-APC |
Product Name | PPAR Gamma (ser273) Polyclonal Antibody, APC Conjugated |
Applications | WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Reactivity | Human, Mouse, Rat, Sheep, Guinea Pig |
Predicted Reactivity | Cow, Chicken, Rabbit |
Specifications | |
Conjugation | APC |
Host | Rabbit |
Source | KLH conjugated synthetic phosphopeptide derived from human PPAR Gamma around the phosphorylation site of ser273 |
Modification Site | ser273 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Gene ID | 5468 |
Swiss Prot | P37231 |
Subcellular location | Cytoplasm, Nucleus |
Synonyms | GLM1; CIMT1; NR1C3; PPARG1; PPARG2; PPARgamma; Peroxisome proliferator-activated receptor gamma; PPAR-gamma; Nuclear receptor subfamily 1 group C member 3; PPARG |
Background | Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. |
Application Dilution | |
WB | 1:300-5000 |
IF(IHC-P) | 1:50-200 |
IF(IHC-F) | 1:50-200 |
IF(ICC) | 1:50-200 |