PTGS2 polyclonal antibody
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- More Files
Western Blot (Cell lysate)
PTGS2 polyclonal antibody (Cat # PAB6096) staining (0.5 ug/mL) of NCI-H460 lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
- Specifications
Product Description
Goat polyclonal antibody raised against synthetic peptide of PTGS2.
Immunogen
A synthetic peptide corresponding to human PTGS2.
Sequence
C-NPTVLLKERSTEL
Host
Goat
Theoretical MW (kDa)
69
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Quality Control Testing
Antibody Reactive Against Synthetic Peptide.
Recommend Usage
ELISA (1:32000)
Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
Western Blot (Cell lysate)
PTGS2 polyclonal antibody (Cat # PAB6096) staining (0.5 ug/mL) of NCI-H460 lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.Enzyme-linked Immunoabsorbent Assay
- Gene Info — PTGS2
Entrez GeneID
5743Protein Accession#
NP_000954.1Gene Name
PTGS2
Gene Alias
COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2
Gene Description
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Omim ID
600262Gene Ontology
HyperlinkGene Summary
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq
Other Designations
OTTHUMP00000033524|cyclooxygenase 2b|prostaglandin G/H synthase and cyclooxygenase|prostaglandin-endoperoxide synthase 2
- Interactomes
- Pathways
- Diseases
- Publication Reference
- Interaction of cyclooxygenases with an apoptosis- and autoimmunity-associated protein.
Ballif BA, Mincek NV, Barratt JT, Wilson ML, Simmons DL.
PNAS 1996 May; 93(11):5544.
Application：IP, Rabbit, Rabbit reticulocyte lysate.
- Interaction of cyclooxygenases with an apoptosis- and autoimmunity-associated protein.