Rat Anti-Mouse CD11b-AF700
Katalog-Nummer 1560-27
Size : 0.1mg
Marke : Southern Biotech
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Telefonnummer : +1 850 650 7790
| Clone | 3A33 |
|---|---|
| Isotype | Rat (Lewis) IgG2aκ |
| Isotype Control | Rat IgG2a-AF700 (KLH/G2a-1-1) |
| Specificity | Mouse CD11b |
| Alternative Names | Integrin αM, Mac-1α, Mac-1, Mo1, CR3, C3biR |
| Description | CD11b (integrin αM subunit) combines with CD18 (integrin β2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils. |
| Immunogen | Peritoneal macrophages from B6D2 hybrid mice |
| Conjugate | AF700 (Alexa Fluor® 700) |
| Buffer Formulation | Phosphate buffered saline containing < 0.1% sodium azide |
| Clonality | Monoclonal |
| Concentration | 0.5 mg/mL |
| Volume | 0.2 mL |
| Recommended Storage | 2-8°C; Avoid exposure to light |
| Trademark Information | Alexa Fluor® is a registered trademark of Thermo Fisher Scientific, Inc. or its subsidiaries |
| Applications | Flow Cytometry – Quality tested 1,4-13 Immunohistochemistry-Frozen Sections – Reported in literature 14 Immunocytochemistry – Reported in literature 2 Immunoprecipitation – Reported in literature 1 Blocking – Reported in literature 3 |
| RRID Number | AB_2794908 |
| Gene ID | 16409 (Mouse) |
| Gene ID Symbol | Itgam (Mouse) |
| Gene ID Aliases | CR3; CR3A; MAC1; Cd11b; Ly-40; Mac-1; Mac-1a; CD11b/CD18; F730045J24Rik |
| UniProt ID | P05555 (Mouse |
| UniProt Name | ITAM_MOUSE (Mouse) |
Documentation
Technical Bulletin Safety Datasheet
Certificate of Analysis Lookup
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