Tauro-Obeticholic acid [863239-61-6]
Katalog-Nummer T13092-25mg
Size : 25mg
Marke : TargetMol
Tauro-Obeticholic acid
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Purity:99.82%
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COA HNMR HPLC
Tauro-Obeticholic acid
Catalog No. T13092Cas No. 863239-61-6
Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR).
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. Pack Size | |
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1 mg | |
5 mg | |
10 mg | |
25 mg | |
50 mg | |
100 mg | |
1 mL x 10 mM (in DMSO) |
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
Description | Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR). |
In vitro | Obeticholic acid and taurine are conjugated in the liver to form taurine-obeticholic acid, which is secreted into the bile. Microorganisms in the ileum and colon can dissociate taurine-cholesteric acid and convert it into the parent drug, which can then be reabsorbed or excreted in feces. |
Molecular Weight | 527.76 |
Formula | C28H49NO6S |
Cas No. | 863239-61-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50 mg/mL (94.74 mM) | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSO
main solution, add 300 μLPEG300
mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O
mix well and clarify
Dose Conversion
You can also refer to dose conversion for different animals. More
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
microorganismsFXRcolonTauro-Obeticholic acidNR1H4TauroObeticholic acidinhibitileumInhibitorTauro Obeticholic acidmetabolite,liver
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