Images
Fluorescent <i>In Situ</i> Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
Application

Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)

Human renal cell carcinoma (FFPE) stained with TFE3 Split FISH Probe. Human renal cell carcinoma showed TFE3 gene split.

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<br>Hybridization position of the probes on the chromosome.
Note


Hybridization position of the probes on the chromosome.


Hybridization position of the probes on the chromosome.

  • Specifications

    Product Description

    Labeled FISH probes for identification of gene split using Fluorescent In Situ Hybridization Technique. ().

    Probe 1

    Name: TFE3(Texas Red)
    Size: Approximately 570kb
    Fluorophore: Texas Red
    Location: Xp11.22

    Probe 2

    Name: TFE3(FITC)
    Size: Approximately 550kb
    Fluorophore: FITC
    Location: Xp11.22

    Probe Gap

    The gap between two probes is approximately 90 kb.

    Origin

    Human

    Source

    Genomic DNA

    Reactivity

    Human

    Form

    Liquid

    Notice

    We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.

    Regulation Status

    For research use only (RUO)

    Quality Control Testing

    Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

    Supplied Product

    DAPI Counterstain (1500 ng/mL ) 125 uL for each 100 uL FISH Probe

    Storage Instruction

    Store at 4°C in the dark.

    Note


    Hybridization position of the probes on the chromosome.

  • Applications

    Fluorescent In Situ Hybridization (Cell)

    Protocol Download

    Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)

    Human renal cell carcinoma (FFPE) stained with TFE3 Split FISH Probe. Human renal cell carcinoma showed TFE3 gene split.
    Protocol Download
  • Gene Info — TFE3

    Entrez GeneID

    7030

    Gene Name

    TFE3

    Gene Alias

    RCCP2, TFEA, bHLHe33

    Gene Description

    transcription factor binding to IGHM enhancer 3

    Omim ID

    314310 605074

    Gene Ontology

    Hyperlink

    Gene Summary

    TFE3, a member of the helix-loop-helix family of transcription factors, binds to the mu-E3 motif of the immunoglobulin heavy-chain enhancer and is expressed in many cell types (Henthorn et al., 1991 [PubMed 1685140]).[supplied by OMIM

    Other Designations

    OTTHUMP00000024272|Renal cell carcinoma, papillary|Transcription factor for IgH enhancer|transcription factor E family, member A|transcription factor E3

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