Thrombin Receptor Agonist
Katalog-Nummer CCP1448-5mg
Size : 5mg
Marke : Cohesion Biosciences
Product Name | Thrombin Receptor Agonist |
Cat No: | CCP1448 |
Source: | Synthetic |
Reactivity: | |
Applications: | |
*Application Key: | |
E- ELISA, WB - Western blot, IH - Immunohistochemistry, IF - Immunofluorescence, FC - Flow cytometry, IC - Immunocytochemistry, IP - Immunoprecipitation, ChIP - Chromatin Immunoprecipitation, EMSA - Electrophoretic Mobility Shift Assay, BL - Blocking, SE - Sandwich ELISA, CBE - Cell-based ELISA, RNAi - RNA interference | |
*Species Reactivity Key: | |
H - Human, M - Mouse, R - Rat, B - Bovine, C - Chicken, D - Dog, G - Goat, Mk - Monkey, P - Pig, Rb - Rabbit, S - Sheep, Z - Zebrafish |
Description: Peptide to Thrombin Receptor Agonist Form: Lyophilized powder Alternative Names: Thrombin Receptor Activator Peptide 14, PAR-1 (1-14) (human), Proteinase Activated Receptor 1 (1-14) (human), Thrombin Receptor (1-14) (human), Coagulation Factor II Receptor (1-14) (human)CAS Number : 137339-65-2Molecular Formula : C81H118N20O23Molecular Weight : 1739.96Purity : > 95%Chemical Structure : H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-OHApplication : Cloning and expression of a functional human thrombin receptor have revealed a protein with seven transmembrane domains and a large extracellular amino-terminal extension. Thrombin cleaves within this extension, thereby creating a new receptor amino-terminus that functions as a tethered ligand and activates the receptor. A 14-amino acid peptide mimicking this new amino-terminus has been found to be a potent thrombin receptor activator as well as an effective agonist for platelet activation.Storage/Stability : Shipped at 4°C. Store at -20°C for one year.