Application 
| IHC-P, E |
|---|---|
| Primary Accession | P45379 |
| Reactivity | Human, Mouse, Rat, Rabbit, Pig, Goat, Bovine, Fish, Dog, Cat |
| Host | Mouse |
| Clonality | Monoclonal |
| Calculated MW | 36kDa |
| Dilution | IHC-P (10 µg/ml) |
| Gene ID | 7139 |
|---|---|
| Other Names | Troponin T, cardiac muscle, TnTc, Cardiac muscle troponin T, cTnT, TNNT2 |
| Target/Specificity | Species cross-reactivity: Cross-reacts with Human, Mouse, Rat, bovine, Cat, canine, Fish, Goat, porcine and Rabbit. |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | TNNT2 / CTNT Antibody (aa146-160) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TNNT2 |
|---|---|
| Function | Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. |
| Tissue Location | Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart |
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Provided below are standard protocols that you may find useful for product applications.
Background
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
References
Mesnard L.,et al.FEBS Lett. 328:139-144(1993).
Townsend P.J.,et al.Genomics 21:311-316(1994).
Townsend P.J.,et al.J. Mol. Cell. Cardiol. 27:2223-2236(1995).
Anderson P.A.,et al.Circ. Res. 76:681-686(1995).
Mesnard L.,et al.Circ. Res. 76:687-692(1995).
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