WDR4 Antibody - C-terminal region : FITC
Katalog-Nummer ARP41321_T100-FITC
Size : 100ul
Marke : Aviva Systems Biology
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Telefonnummer : +1 850 650 7790
WDR4 Antibody - C-terminal region (ARP41321_T100)
| Datasheets/Manuals | Printable datasheet for anti-WDR4 (ARP41321_T100) antibody |
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| Tested Species Reactivity | Human |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Horse, Pig, Rabbit, Yeast |
| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Application | IHC, WB |
| Reconstitution and Storage | For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
| Immunogen | The immunogen is a synthetic peptide directed towards the C terminal region of human WDR4 |
| Purification | Protein A purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 93%; Horse: 93%; Human: 100%; Mouse: 87%; Pig: 90%; Rabbit: 83%; Rat: 75%; Yeast: 75% |
| Peptide Sequence | Synthetic peptide located within the following region: AGADASFSSLYKATFDNVTSYLKKKEERLQQQLEKKQRRRSPPPGPDGHA |
| Concentration | 1.0 mg/ml |
| Blocking Peptide | For anti-WDR4 (ARP41321_T100) antibody is Catalog # AAP41321 (Previous Catalog # AAPP22676) |
| Subunit | WDR4 |
| Reference | Michaud,J., (2000) Genomics 68 (1), 71-79 |
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| Gene Symbol | WDR4 |
| Gene Full Name | WD repeat domain 4 |
| Alias Symbols | hWH, Wuho, MIGSB, TRM82, GAMOS6, TRMT82 |
| NCBI Gene Id | 10785 |
| Protein Name | tRNA (guanine-N(7)-)-methyltransferase subunit WDR4 |
| Description of Target | WDR4 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes.This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Two transcript variants encoding the same protein have been found for this gene. |
| Uniprot ID | P57081 |
| Protein Accession # | NP_387510 |
| Nucleotide Accession # | NM_033661 |
| Protein Size (# AA) | 412 |
| Molecular Weight | 45kDa |
| Protein Interactions | FAM118A; RABGGTB; METTL1; LGR4; CUL5; PDE12; WDR92; DCTPP1; P3H1; ELAC2; XPO5; NPLOC4; UBE2R2; DPP8; PPME1; ERO1L; UBQLN2; DBNL; KIAA1279; ARIH1; HSPBP1; PLIN3; ACTR2; SAE1; ASMTL; OGT; SURF2; SRP14; DNAJB1; DDX5; ALAD; ADSL; ERC1; UBP1; UBE2D1; TERF2; TE |
