• Specifications

    Product Description

    Rabbit polyclonal antibody raised against synthetic peptide of WNK4.

    Immunogen

    A synthetic peptide corresponding to residues within 200-300 of human WNK4.

    Host

    Rabbit

    Reactivity

    Human, Mouse, Rat

    Specificity

    This antibody is useful for Western blot where a band is seen at ~135-155 kD.

    Form

    Liquid

    Conjugation

    DyLight 650

    Purification

    Immunogen affinity purification

    Recommend Usage

    Western Blot (2 ug/ mL)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In 50 mM sodium borate (0.05% sodium azide).

    Storage Instruction

    Store at 4°C in the dark.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Western Blot

  • Gene Info — WNK4

    Entrez GeneID

    65266

    Protein Accession#

    Q96J92

    Gene Name

    WNK4

    Gene Alias

    PHA2B, PRKWNK4

    Gene Description

    WNK lysine deficient protein kinase 4

    Omim ID

    145260 601844

    Gene Ontology

    Hyperlink

    Gene Summary

    This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB

    Other Designations

    protein kinase, lysine deficient 4

  • Diseases