Glucose-6-phosphate dehydrogenase is a crucial enzyme in the pentose phosphate pathway, responsible for catalyzing the conversion of glucose-6-phosphate to 6-phosphoglucono-δ-lactone while reducing NADP⁺ to NADPH. This reaction plays a vital role in cellular metabolism and the protection of red blood cells against oxidative stress. Glucose-6-phosphate dehydrogenase deficiency is a common genetic disorder that can lead to hemolytic anemia, particularly under oxidative stress or exposure to certain drugs. Therefore, accurate measurement of Glucose-6-phosphate dehydrogenase activity is essential for diagnosing this condition.

The glucose-6-phosphate dehydrogenase activity assay is a reliable and efficient tool designed for the quantification of Glucose-6-phosphate dehydrogenase activity in various biological samples, including serum, plasma, urine, and cell extracts.