Anti-Atg16L (Human) pAb

Katalog-Nummer PM040

Size : 100ug

Marke : MBL International

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Anti-Atg16L pAb
Anti-Atg16L pAb
PM040
Antibody
100 uL

DATA SHEET

Polyclonal Antibody targeting Atg16L for ICC, IP, WB.

TargetAtg16L
Product TypeAntibody
ApplicationICC, IP, WB
ClonalityPolyclonal
ConjugateUnlabeled
IsotypeAffinity Purified Ig
ImmunogenRecombinant human ATG16L1 TV2 (85-588 a.a.)
Host SpeciesRabbit
Species ReactivityHuman, Hamster, Mouse, Rat
FormulationPBS containing 50% glycerol, pH 7.2. No preservative is contained.
Research AreaCancer, Immunology, Autophagy
Description/Background

Autophagy is a process of intracellular bulk degradation in which cytoplasmic components including organelles are sequestered within double-membrane vesicles that deliver the contents to the lysosome/vacuole for degradation. Autophagy has two ubiquitin-like conjugation systems, the Atg12 and LC3-II systems. In the Atg12 conjugation system, the Atg16L-Atg12-Atg5 forms 800 kDa complex that elongate autophagic isolation membrane. After completion of the formation of the autophagosome, the Atg12-Atg5-Atg16L complex dissociates from the membrane. In recent study, nonsynonymous SNP analysis has indicated that ATG16L1 is a Crohn’s disease susceptibility gene.

Storage Temperature-20°C
ProtocolsICC, IP, WB
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
PM040
Antibody
100 uL

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