Both Classical (MC catalog codes) and Encapsulated (ME catalog codes) superparamagnetic microspheres are synthesized using a process that results in the distribution of iron oxide crystals throughout the polymer matrix. The surfaces of Encapsulated magnetic microspheres are expected to be free of iron oxide, while the Classical version will have some exposed iron oxide. COMPEL microspheres (UMC catalog codes) are highly uniform and spherical. Fluorescent magnetic microspheres are available as ~1% solids (w/v) aqueous suspensions in four standard volumes: 1mL, 5mL, 10mL, and 100mL.
PDS 731, Fluorescent Microspheres
PDS 705, COMPEL™ Microspheres
TSD 0748, Fluorescent Magnetic Particles for Cell Labeling and Tracking
Fluorescence Spectra
SDS MF220, (MC and ME Fluorescent Magnetic)
SDS MF221, (COMPEL™ Fluorescent)
| Catalog Number | Description | Fluorescence Color | Nominal Diameter | Specification Range |
|---|---|---|---|---|
| MCDG001 | Classical Magnetic Polymer-COOH | Dragon Green | 0.9µm | 0.50 - 2.00µm |
| MCFR001 | Classical Magnetic Polymer-COOH | Flash Red | 0.9µm | 0.50 - 2.00µm |
| MEDG002 | Encapsulated Magnetic Polymer-COOH | Dragon Green | 1.63µm | 0.50 - 2.00µm |
| MESY002 | Encapsulated Magnetic Polymer-COOH | Suncoast Yellow | 1.63µm | 0.50 - 2.00µm |
| MEGB002 | Encapsulated Magnetic Polymer-COOH | Glacial Blue | 1.63µm | 0.50 - 2.00µm |
| MEFR002 | Encapsulated Magnetic Polymer-COOH | Flash Red | 1.63µm | 0.50 - 2.00µm |
| UMGB001 | COMPEL™ Magnetic COOH modified | Glacial Blue | 3µm | 2.50 - 3.50µm |
| UMDG001 | COMPEL™ Magnetic COOH modified | Dragon Green | 3µm | 2.50 - 3.50µm |
| UMEG001 | COMPEL™ Magnetic COOH modified | Envy Green | 3µm | 2.50 - 3.50µm |
| UMFR001 | COMPEL™ Magnetic COOH modified | Flash Red | 3µm | 2.50 - 3.50µm |
| UMGB002 | COMPEL™ Magnetic COOH modified | Glacial Blue | 6µm | 5.50 - 6.50µm |
| UMDG002 | COMPEL™ Magnetic COOH modified | Dragon Green | 6µm | 5.50 - 6.50µm |
| UMFR002 | COMPEL™ Magnetic COOH modified | Flash Red | 6µm | 5.50 - 6.50µm |
| UMGB003 | COMPEL™ Magnetic COOH modified | Glacial Blue | 8µm | 7.50 - 8.50µm |
| UMDG003 | COMPEL™ Magnetic COOH modified | Dragon Green | 8µm | 7.50 - 8.50µm |
| UMFR003 | COMPEL™ Magnetic COOH modified | Flash Red | 8µm | 7.50 - 8.50µm |
References
Hill, J, Dick, A, Raman, J V, Thompson. R , Yu. Z , Hinds, K ,…Lederman, R (2003) Serial Cardiac Magnetic Resonance Imaging of Injected Mesenchymal Stem Cells Circulation.108:1009-1014
Shapiro E M, Sharer K, Skrtic S, and Koretsky, A. P. (2006) In vivo detection of single cells by MRI. Magn. Reson. Med., 55: 242–249
Shapiro, E M, Medford-Davis, L N, Fahmy, TM, Dunbar, CE, Koretsky, AP (2007 Antibody-mediated cell labeling of peripheral T cells with micron-sized iron oxide particles (MPIOs) allows single cell detection by MRI. Contrast Media Mol Imaging, 2: 147–153
Shapiro, E M, Gonzalez-Perez, O, García-Verdugo, JM, Alvarez-Buylla, A, Koretsky, AP (2006) Magnetic resonance imaging of the migration of neuronal precursors generated in the adult rodent brain. NeuroImage, 32(3), 1150–1157