Mouse Anti-Human CD19-PE/CY5.5
Katalog-Nummer 9340-16
Size : 100tests
Marke : Southern Biotech
Clone | SJ25-C1 |
---|---|
Isotype | Mouse (BALB/c) IgG1κ |
Isotype Control | 0102-16 |
Specificity | Human CD19 |
Alternative Names | B4, B-lymphocyte antigen, Leu-12 |
Description | CD19 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is expressed at all stages of B cell differentiation except terminally differentiated plasma cells. It is also present on the cell surface of follicular dendritic cells. CD19 associates with CD21, CD81, Leu 13 and/or MHC Class II molecules to form a signal transduction complex on the B cell surface. This signaling complex modulates the activation threshold for the B cell antigen receptor (BCR). |
Immunogen | NALM-1 and NALM-16 leukemia cell line |
Conjugate | PE/CY5.5 (R-phycoerythrin/Cyanine 5.5) |
Buffer Formulation | Phosphate buffered saline containing < 0.1% sodium azide and a stabilizer |
Clonality | Monoclonal |
Concentration | Lot specific |
Volume | 1.0 mL |
Recommended Storage | 2-8°C; Avoid exposure to light; Do not freeze |
Trademark Information | Cy® is a registered trademark of Global Life Sciences Solutions Germany GmbH |
Applications | Flow Cytometry – Quality tested 5-13 Immunohistochemistry-Frozen Sections – Reported in literature 1 Immunoprecipitation – Reported in literature 2 Blocking – Reported in literature 3,4 |
RRID Number | AB_2796746 |
Gene ID | 930 (Human) |
Gene ID Symbol | CD19 (Human) |
Gene ID Aliases | B4; CVID3 |
UniProt ID | P15391 (Human |
UniProt Name | CD19_HUMAN (Human) |
Documentation
Technical Bulletin Safety Datasheet
Certificate of Analysis Lookup
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- 4. de Rie MA, Terpstra FG, van Lier RA, von dem Borne AE, Miedema F. Identification of functional epitopes on workshop-defined B-cell membrane molecules. In: McMichael AJ, Beverley PC, Cobbold S, Crumpton MJ, Gilks W, Gotch FM, et al, editors. Leukocyte Typing III: White Cell Differentiation Antigens. Oxford: Oxford University Press; 1987. p. 402-5. (Block)
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- 7. Henneken M, Dörner T, Burmester G, Berek C. Differential expression of chemokine receptors on peripheral blood B cells from patients with rheumatoid arthritis and systemic lupus erythematosus. Arthritis Res Ther. 2005;7:R1001-13. (FC)
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