Mouse Anti-Human ZAP-70-UNLB
Katalog-Nummer 10650-01S
Size : 25μg
Marke : Southern Biotech
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Telefonnummer : +1 850 650 7790
| Clone | SBZAP |
|---|---|
| Isotype | Mouse (BALB/c) IgG1κ |
| Isotype Control | Mouse IgG1-UNLB (15H6) |
| Specificity | Human ZAP-70 |
| Alternative Names | Tyrosine-protein kinase ZAP-70, zeta-chain-associated protein kinase 70, Syk-related tyrosine kinase |
| Description | ZAP-70 is a protein tyrosine kinase (PTK) with the primary role of catalyzing the phosphorylation of tyrosine residues in cellular proteins, and thus, contributes significantly to the initiation of cell signaling. ZAP-70 is normally expressed on T cell and NK cells. |
| Immunogen | Human ZAP-70 (a.a. 280-309) |
| Conjugate | UNLB (Unconjugated) |
| Buffer Formulation | Borate buffered saline, pH 8.2 |
| Clonality | Monoclonal |
| Concentration | 0.1 mg/mL |
| Volume | 0.25 mL or 1.0 mL |
| Recommended Storage | 2-8°C |
| Applications | Flow Cytometry – Quality tested 1-20 ELISA – Quality tested |
| RRID Number | AB_2794399 |
| Gene ID | 7535 (Mouse) |
| Gene ID Symbol | ZAP70 (Mouse) |
| Gene ID Aliases | ADMIO2; IMD48; SRK; STCD; STD; TZK; ZAP-70 |
| UniProt ID | P43403 (Human |
| UniProt Name | ZAP70_HUMAN (Human) |
Documentation
Technical Bulletin Safety Datasheet
Certificate of Analysis Lookup
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- 8. Degheidy HA, Venzon DJ, Farooqui MZ, Abbasi F, Arthur DC, Wilson WH, et al. Improved ZAP-70 assay using two clones, multiple methods of analysis and clinical correlation. Cytometry B Clin Cytom. 2011;80:309-17. (FC)
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- 18. Abousamra NK, El-Din MS, Elzahaf EH, Esmael ME. Ectonucleoside triphosphate diphosphohydrolase-1 (E-NTPDase1/CD39) as a new prognostic marker in chronic lymphocytic leukemia. Leuk Lymphoma. 2015;56:113-9. (FC)
- 19. Lafarge ST, Li H, Pauls SD, Hou S, Johnston JB, Gibson SB, et al. ZAP70 expression directly promotes chronic lymphocytic leukaemia cell adhesion to bone marrow stromal cells. Br J Haematol. 2015;168:139-42. (FC)
- 20. Lafarge ST, Hou S, Pauls SD, Johnston JB, Gibson SB, Marshall AJ. Differential expression and function of CD27 in chronic lymphocytic leukemia cells expressing ZAP-70. Leuk Res. 2015;39:773-8. (FC)
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