NMDAR2A (Ser1232) Polyclonal Antibody, FITC Conjugated
Katalog-Nummer bs-19290R-FITC
Size : 100ul
Marke : Bioss
NMDAR2A (Ser1232) Polyclonal Antibody, FITC Conjugated
Applications
Predicted Reactivity
Overview | |
Catalog # | bs-19290R-FITC |
Product Name | NMDAR2A (Ser1232) Polyclonal Antibody, FITC Conjugated |
Applications | IF(IHC-P), IF(IHC-F), IF(ICC) |
Specificity | This phosphorylated site is homologous to that of Ser1232 in Mouse and Rat. |
Predicted Reactivity | Human, Mouse, Rat, Pig, Horse, Rabbit |
Specifications | |
Conjugation | FITC |
Host | Rabbit |
Source | KLH conjugated Synthesised phosphopeptide derived from human NMDAR2A around the phosphorylation site of Ser1232 |
Modification Site | Ser1232 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Gene ID | 2903 |
Swiss Prot | Q12879 |
Subcellular location | Cell membrane |
Synonyms | NMDAR2A (phospho S1232); p-NMDAR2A (phospho S1232); GRIN2B; Glutamate [NMDA] receptor subunit epsilon 1; Glutamate [NMDA] receptor subunit epsilon 2; Glutamate [NMDA] receptor subunit epsilon-1; Glutamate [NMDA] receptor subunit epsilon-2; GRIN2A; hNR2A; hNR3; N methyl D aspartate receptor subtype 2A; N methyl D aspartate receptor subtype 2B; N-methyl D-aspartate receptor subtype 2A; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 3; NMDAR2A; NMDAR2B; NMDE2_HUMAN; NR2A; NR2B; NR3. |
Background | This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants. |
Application Dilution | |
IF(IHC-P) | 1:50-200 |
IF(IHC-F) | 1:50-200 |
IF(ICC) | 1:50-200 |