Recombinant Feline TNF alpha

Bulk quantities of Feline TNFα protein are available.
Please for pricing.

Feline TNFα Specifications

Molecular Weight (calculated) - 17.2kDa

Amino Acid Sequence - LRSSSRTPSD KPVAHVVANP EAEGQLQWLS RRANALLANG VELTDNQLKV PSDGLYLIYS QVLFTGQGCP STHVLLTHTI SRFAVSYQTK VNLLSAIKSP CQRETPEGAE AKPWYEPIYL GGVFQLEKGD RLSAEINLPA YLDFAESGQV YFGIIAL (157)

Gene ID - 493755

Homology Across Species
Felis catus (domestic cat) TNFα – 100%
Panthera tigris altaica (Amur tiger) TNFα – 99%
Panthera pardus (leopard) TNFα – 99%
Acinonyx jubatus (cheetah) TNFα – 99%
Leptonychotes weddellii (Weddell seal) TNFα – 96%
Ursus maritimus (polar bear) TNFα – 96%
Odobenus rosmarus divergens (Pacific walrus) TNFα – 96%
Vulpes vulpes (red fox) TNFα – 96%
Mirounga angustirostris (Northern elephant seal) TNFα – 96%
Ailuropoda melanoleuca (giant panda) TNFα – 95%
Mustela putorius furo (domestic ferret) TNFα – 95%
Trichechus manatus latirostris (Florida manatee) TNFα – 95%
More - https://blast.ncbi.nlm.nih.gov/

Endotoxin - Naturally endotoxin-free

Applications

Cell Culture, ELISA Standard, Western Blot Control

TNFα Background

Tumor necrosis factor alpha (TNFSF2) is a member of the TNF Superfamily. It is produced chiefly by activated macrophages, but it is produced also by a broad variety of cell types including lymphoid cells, mast cells, endothelial cells, cardiac myocytes, adipose tissue, fibroblasts, and neuronal tissue. The primary role of TNF alpha is in the regulation of immune cells. TNF alpha, being an endogenous pyrogen, is able to induce fever, to induce apoptotic cell death, to induce sepsis (through IL-1 & IL-6 production), to induce cachexia, induce inflammation, and to inhibit tumorigenesis and viral replication.

Alternate Names - TNF, DIF, TNF-alpha, TNFA, TNFSF2, Tumour necrosis factor, TNF-α, tumor necrosis factor, TNLG1F, Tumor necrosis factor alpha