Reagenzien und Instrumente für die Immunologie Zellbiologie und Molekularbiologie
 

Canvax Biotech


Canvax is a leading manufacturer and supplier of the most innovative solutions, kits and R&D Reagents inside Molecular Biology fields. Since its foundation in 2001, Canvax offers reliable, cost-effective and easy-to-use innovative tools for research.

Based in Córdoba (Spain), since its beginning it has focused on R&D of multiplex high throughput platforms (HTS) for Drug discovery and Diagnostic applied biosensors. Over a decade later, Canvax is a worldwide leading expert in GPCR expression in heterologous cells, with important patents and exclusive know-how. Canvax prides itself to be the first company to get an unprecedented milestone that could revolutionize the Diagnostics sector: Canvax established stable high-level expression of odour GPCRs into heterologous cell lines in 2014.

This key milestone, that could be applied in diagnostic, perfume and cosmetic industry, are being employed to obtain a molecular nose, a sensitive and non-invasive diagnostic molecular device for early detection of cancer, as the nose of trained dogs do. Thanks to this project, Canvax was awarded, in 2013, with the largest Public & Private Contract for Pre competitive Technology Development in Spanish history.

 
> Canvax Biotech > Produkte für die Forschung > Molekularbiologische Werkzeuge > Cloning tools > Competent cells
Competent cells

Competent cells


Cellular competence refers to a cell's ability to absorb foreign (extracellular) DNA from its environment. The process of genetic absorption is called transformation. In some cases, the genetic material absorbed by a cell may be incorporated, or recombined, into its own genome. This incorporation of genetic material into the host genome is called horizontal gene transfer (HGT) or lateral gene transfer.
Natural competence and gene transfer have facilitated many adaptations in prokaryotic and eukaryotic cells. Competent cells can either occur naturally or be made competent artificially.
There are two types of artificially competent cells: chemically competent cells and electro-competent cells. Chemically competent cells are cells that have been made competent by a salt treatment followed by a heat shock step. Electro-competent cells are made competent by using an electrical impulse from an electroporator to create temporary pores (poration) in the cell membrane of prokaryotic or eukaryotic cells.

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