SARS-CoV-2 - ELISA kits - Spike protein
The SARS-CoV-2 virus, the cause of the current Covid-19 pendemia, can infect human respiratory epithelial cells through an interaction with the human ACE2 receptor or angiotensin converting enzyme receptor 2. SARS-CoV-2 has on its surface a protein called Spike or S protein. This type I transmembrane protein is present on the viral envelope in the form of a homotrimer. Each monomer consists of 2 subunits, S1 and S2. The S1 subunit contains a receptor binding domain (RBD) which binds to the ACE2 receptor on the host membrane. The S2 sub-unit is activated by the bond between S1 and the ACE2 receptor and contains the elements necessary for membrane fusion. The S protein thus plays an important role in the infection of SARS-CoV-2 as well as in the induction of neutralizing antibody and T cell responses and in protective immunity.
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RUOCE / IVD
- Biotin 8
- HRP 5
- SARS-CoV-2 4
- COVID-19 1
- Unconjugated 1
- virus 391
- human 99
- mouse 16
- rat 10
- hamster 4
- monkey 4
- pig 4
- all species 2
- rabbit 2
- ELISA/ELISPOT
- human 8
- virus 2
- ELISA 610
- Sandwich ELISA 6
- 32.22 pg/mL 3
- 6.5 pg/ml 3
- 163.1 pg/ml 1
- 182.1 pg/ml 1
- < 0.1 EU/μg of the protein by LAL method. 1
- < 1.0 EU/μg of the protein by LAL method. 1
- Neutralizing/Inhibition 1
- 1A9 / HL263 1
- HL1014 / HL1003 1
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Beschreibung
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abx395200-96tests
96tests
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