AG Scientific
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AG Scientific ist auf sekundäre Metaboliten aus der Fermentation spezialisiert. Die meisten ihrer Produkte sind Antibiotika für die Genselektion, aber der Katalog umfasst auch antimikrobielle, antimykotische, krebshemmende, antivirale, antiparasitäre und immunsuppressive Reagenzien.
Antibiotika:
AG Scientific, Inc. hat eine Reihe von antibiotischen Screening-Mitteln entwickelt, darunter Blasticidin S, G-418, Puromycin, Gentamycin, Kanamycin, Ampicillin, Streptomycin und Carbenicillin.
In jüngster Zeit hat AG Scientific Partnerschaften mit pharmazeutischen Kunden geschlossen, die die CRISPR-Technologie nutzen.
Anti-Krebs:
Der Katalog umfasst sekundäre Metaboliten im Bereich der Krebsbekämpfung wie Rapamycin, FK-506, Cyclosporin A.
Website : www.agscientific.com
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Aristolochic Acid
Aristolochic acid, inherent in the Aristolochiaceae plant family, stands as a subject of profound interest in immunology, cell biology, and molecular biology. This nitrophenanthrene carboxylic acid, encompassing variants such as aristolochic acid I and II, possesses a distinctive chemical structure that intertwines with intricate biological processes.
In immunology, research delves into the compound's potential immunomodulatory effects, shedding light on its role in endosomal acidification and immune cell activation. Concurrently, in cell biology, aristolochic acid's impact on intracellular pH dynamics, enzymatic activities, and membrane transport contributes to the understanding of cellular homeostasis.
At the molecular level, aristolochic acid’s unique structure influences nucleic acids and proteins, unveiling its significance in DNA replication, transcription, and translation. Scientific endeavors, guided by meticulous analytical techniques, aim to unravel the molecular mechanisms underpinning its actions.
Recognizing the dual nature of aristolochic acid, from historical applications in traditional medicine to contemporary health concerns, this article navigates through its complexities. The synthesis of immunological, cellular, and molecular perspectives underscores the compound’s pivotal role in the intricate landscape of biological research.