1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine [26662-94-2]

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine (POPE) is a phospholipid that plays a critical role in the structure and function of cellular membranes. It is used extensively in biochemical and biophysical research to study membrane dynamics, lipid-protein interactions, and the properties of lipid bilayers. POPE is a major component of the lipid bilayer in many types of cells and is instrumental in modulating membrane fluidity and phase behavior. In experimental setups, POPE is often incorporated into model membranes or liposomes to investigate the mechanics of membrane fusion, vesicle formation, and the impact of various proteins on lipid bilayer properties. Researchers also utilize POPE to explore the interactions between phospholipids and membrane-associated proteins, which are crucial for understanding signal transduction pathways and membrane trafficking in cells. These studies are purely scientific, focusing on fundamental aspects of cell biology and biophysics. The origin and purity of POPE are critical factors that are stringently verified to ensure reliability in experimental outcomes, facilitating precise measurements and observations in research dedicated to uncovering the roles of lipids in cellular membranes.

References:

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