Reagenzien und Instrumente für die Immunologie Zellbiologie und Molekularbiologie
 
> 1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine [89947-80-8]

1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine [89947-80-8]

Drucken Drucken
Melden Sie sich an

Katalog-Nummer HY-154857-1mg

Size : 1mg

Marke : MedChemExpress

Contact local distributor :


Telefonnummer : +1 850 650 7790

1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine is a glycerophosphorylcholine, consisting of glycerol phosphate, choline and palmitic acid. It accumulates in vivo at sites of oxidative stress. 1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine may be a ligand of scavenger receptors class B, while oxidized phospholipids oxPC(CD36) are potent ligands of scavenger receptors class B (CD36 and SR-BI). Oxidized phospholipids (oxPLs) also play an important role in tumor apoptosis, may be elevated in malignant biliary strictures.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine Chemische Struktur

1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine Chemische Struktur

CAS. Nr. : 89947-80-8

This product is a controlled substance and not for sale in your territory.

Beschreibung

1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine is a glycerophosphorylcholine, consisting of glycerol phosphate, choline and palmitic acid. It accumulates in vivo at sites of oxidative stress. 1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine may be a ligand of scavenger receptors class B, while oxidized phospholipids oxPC(CD36) are potent ligands of scavenger receptors class B (CD36 and SR-BI). Oxidized phospholipids (oxPLs) also play an important role in tumor apoptosis, may be elevated in malignant biliary strictures[1][2].

IC50 & Target

CD36[2]
Molekulargewicht

595.70

Formel

C28H54NO10P
CAS. Nr.

89947-80-8
Appearance

Solid

Color

White to off-white

SMILES

C[N+](C)(C)CCOP(OC[C@H](OC(CCC(O)=O)=O)COC(CCCCCCCCCCCCCCC)=O)([O-])=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Reinheit & Dokumentation
Verweise

  • [1]. Navaneethan U, et al Lipidomic profiling of bile in distinguishing benign from malignant biliary strictures: a single-blinded pilot study. Am J Gastroenterol. 2014 Jun;109(6):895-902.  [Content Brief]

    [2]. Gao D, et al. Structural basis for the recognition of oxidized phospholipids in oxidized low density lipoproteins by class B scavenger receptors CD36 and SR-BI. J Biol Chem. 2010 Feb 12;285(7):4447-54.  [Content Brief]

  • [1]. Navaneethan U, et al Lipidomic profiling of bile in distinguishing benign from malignant biliary strictures: a single-blinded pilot study. Am J Gastroenterol. 2014 Jun;109(6):895-902.

    [2]. Gao D, et al. Structural basis for the recognition of oxidized phospholipids in oxidized low density lipoproteins by class B scavenger receptors CD36 and SR-BI. J Biol Chem. 2010 Feb 12;285(7):4447-54.

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine Related Classifications

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine89947-80-8Othersglycerophosphorylcholineglycerol phosphatecholine and palmitic acidoxidative stressscavenger receptors class BCD36SR-BItumor apoptosismalignant biliary stricturesInhibitorinhibitorinhibit