ALDH1A1 Rabbit Polyclonal Antibody
Katalog-Nummer TA321182
Size : 100ul
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| Product Data | |
| Application | IHC, WB |
|---|---|
| Application | WB: 500-1000 WB positive control: Human liver cancer tissue IHC: 20-50 Positive control: Human colon cancer Predicted cell location: Cytoplasm |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to C terminal 290 amino acids of Human Aldehyde dehydrogenase 1 family, member A2 |
| Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 57 kDa |
| Gene Name | aldehyde dehydrogenase 1 family member A1 |
| Database Link | |
| Background | This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. |
| Synonyms | ALDC; ALDH-E1; ALDH1; ALDH11; HEL-9; HEL-S-53e; HEL12; PUMB1; RALDH1 |
| Reference Data | |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
| Protein Pathways | Metabolic pathways, Retinol metabolism |
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