General Info
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | SARS-CoV-2 |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-SARS-CoV-2-Spike ECD (11-1208) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | ELISA 1:20000-1:80000WB 1:2000-1:6000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
| Immunogen Region: | 11-1208 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 11-1208 of coronavirus Spike ECD (YP_009724390.1). |
| Immunogen Sequence: | VSSQCVNLTTRTQLPPAYTN SFTRGVYYPDKVFRSSVLHS TQDLFLPFFSNVTWFHAIHV SGTNGTKRFDNPVLPFNDGV YFASTEKSNIIRGWIFGTTL DSKTQSLLIVNNATNVVIKV CEFQFCNDPFLGVYYHKNNK SWMESEFRVYSSANNCTFEY VSQPFLMDLEGKQGNFKNLR EFVFKNIDGYFKIYSKHTPI NLVRDLPQGFSALEPLVDLP IGINITRFQTLLALHRSYL |
Description
| Background | The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance