Images
Flow Cytometry
Application

Flow Cytometry

Flow cytometric analysis of Ramos cells with BTK (phospho Y551) monoclonal antibody, clone G12 (PE) (Cat # MAB18833). Unstained untreated cells as negative control (blue) or stained untreated (red) or treated with pervanadate (green).

  • Specifications

    Product Description

    Rabbit monoclonal antibody raised against synthetic phosphopeptide of human BTK.

    Immunogen

    A synthetic phosphopeptide corresponding to residues surrounding Y551 of human BTK.

    Host

    Rabbit

    Reactivity

    Human

    Form

    Liquid

    Conjugation

    PE

    Purification

    Protein A/G purification

    Isotype

    IgG1, kappa

    Recommend Usage

    Flow Cytometry (5 uL/106 cells)
    The optimal working dilution should be determined by the end user.

    Storage Buffer

    In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).

    Storage Instruction

    Store at 4°C.

    Note

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

  • Applications

    Flow Cytometry

    Flow cytometric analysis of Ramos cells with BTK (phospho Y551) monoclonal antibody, clone G12 (PE) (Cat # MAB18833). Unstained untreated cells as negative control (blue) or stained untreated (red) or treated with pervanadate (green).
  • Gene Info — BTK

    Entrez GeneID

    695

    Gene Name

    BTK

    Gene Alias

    AGMX1, AT, ATK, BPK, IMD1, MGC126261, MGC126262, PSCTK1, XLA

    Gene Description

    Bruton agammaglobulinemia tyrosine kinase

    Omim ID

    300300 307200

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. [provided by RefSeq

    Other Designations

    B-cell progenitor kinase|Bruton tyrosine kinase|OTTHUMP00000023676|OTTHUMP00000063593|agammaglobulinemia tyrosine kinase|dominant-negative kinase-deficient Brutons tyrosine kinase|tyrosine-protein kinase BTK

  • Interactomes
  • Pathways
  • Diseases