C5a anaphylatoxin Polyclonal Antibody, PE-Cy7 Conjugated
Katalog-Nummer bs-0324R-PE-Cy7
Size : 100ul
Marke : Bioss
C5a anaphylatoxin Polyclonal Antibody, PE-Cy7 Conjugated
Applications
Reactivity
Predicted Reactivity
Overview | |
Catalog # | bs-0324R-PE-Cy7 |
Product Name | C5a anaphylatoxin Polyclonal Antibody, PE-Cy7 Conjugated |
Applications | WB |
Reactivity | Human, Mouse |
Predicted Reactivity | Rat |
Specifications | |
Conjugation | PE-Cy7 |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from mouse C5a (725-770aa) |
Immunogen Range | 701-755/1680 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Gene ID | 15139 |
Swiss Prot | P06684 |
Subcellular location | Secreted |
Synonyms | C5; He; C5a; Complement C5; Hemolytic complement; Hc |
Background | Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation. |
Application Dilution | |
WB | 1:300-5000 |