Caspase 5 (Ich-3, ICErel-III, TY) (AP)

Katalog-Nummer C2087-24M-AP-100ul

Size : 100ul

Marke : US Biological

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C2087-24M-AP Caspase 5 (Ich-3, ICErel-III, TY) (AP)

Clone Type
Polyclonal
Host
rabbit
Source
human
Isotype
IgG
Grade
Affinity Purified
Applications
WB
Crossreactivity
Bo Hm Hu Mk Mo Rb Rt
Shipping Temp
Blue Ice
Storage Temp
4°C

Caspase 5/Ich-3/Ty/ICErel-III belongs to the ICE family of cysteine proteases. Its expression is enhanced during the septic shock. Over-expression of Caspase 5 can induce apoptosis. It is processed through Granzyme-B. ||Applications:|Suitable for use in Western Blot. Other applications not tested.||Recommended Dilution:|Western Blot: 2.5-5ug/ml for 2hrs at RT|Optimal dilutions to be determined by the researcher.||Positive Control: Jurkat cells ||Storage and Stability:|May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. ||Note: Applications are based on unconjugated antibody.

Applications
Product Type: Pab|Isotype: IgG|Host: rabbit|Source: human|Concentration: As reported|Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).|Purity: Purified by Protein A affinity chromatography.|Immunogen: A synthetic peptide derived from the middle of human Caspase 5.|Epitope: Middle region Cellular Localization: Cytoplasmic|Specificity: Recognizes Caspase 5. May recognize p38 and p30 cleavage determinants. MW of Antigen: 42-47kD Species Crossreactivity: Human, mouse, rat, bovine monkey, rabbit and hamster.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
A synthetic peptide derived from the middle of human Caspase 5.|Epitope: Middle region Cellular Localization: Cytoplasmic
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Purity
Purified by Protein A affinity chromatography.
Specificity
Recognizes Caspase 5. May recognize p38 and p30 cleavage determinants. MW of Antigen: 42-47kD Species Crossreactivity: Human, mouse, rat, bovine monkey, rabbit and hamster.
References
1. Wang S, et. al. (1996) J Biol Chem, 271:20580- 20587. 2. Munday N, et. al. (1995) J Biol Chem, 270:15870–15876.