CD200 Receptor 1 (Cd200r1, Cell Surface Glycoprotein CD200 Receptor 1, CD200 Cell Surface Glycoprotein Receptor, Cell Surface Glycoprotein OX2 Receptor 1, Mox2r, OX102 Antigen, Ox2r) (APC)

Katalog-Nummer C2548-96D-APC-100ul

Size : 100ul

Marke : US Biological

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C2548-96D-APC CD200 Receptor 1 (Cd200r1, Cell Surface Glycoprotein CD200 Receptor 1, CD200 Cell Surface Glycoprotein Receptor, Cell Surface Glycoprotein OX2 Receptor 1, Mox2r, OX102 Antigen, Ox2r) (APC)

Clone Type
Polyclonal
Host
mouse
Source
rat
Isotype
IgG1
Grade
Affinity Purified
Applications
IHC IP WB
Crossreactivity
Rt
Shipping Temp
Blue Ice
Storage Temp
4°C Do Not Freeze

CD200 is expressed by a subset of B lymphocytes, some endothelial cells and by neurons. Recent studies have suggested that the CD200-CD200 ligand system is of importance in the control of macrophage and granulocyte activation.||Applications: |Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.||Recommended Dilutions:|Optimal dilutions to be determined by the researcher.||Hybridoma:|Spleen cells from immunized BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.||Storage and Stability:|Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. ||Note: Applications are based on unconjugated antibody.

Applications
Product Type: Mab|Isotype: IgG1|Clone No: OX-102|Host: mouse|Source: rat|Concentration: As Reported|Form: Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).|Purity: Purified by Protein G affinity chromatography from tissue culture supernatant.|Immunogen: Membrane fraction of thioglycollate-elicited rat peripheral cells.|Specificity: Recognizes the rat OX2 (CD200) receptor 1. This antigen is a heavily glycosylated 60­100kD cell surface molecule expressed by cells of the myeloid lineage but not by T or B lymphocytes. This antibody has been shown to block the interaction of OX2 receptor 1 with CD200.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
Membrane fraction of thioglycollate-elicited rat peripheral cells.
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with Allophycocyanin (APC).
Purity
Purified by Protein G affinity chromatography from tissue culture supernatant.
Specificity
Recognizes the rat OX2 (CD200) receptor 1. This antigen is a heavily glycosylated 60­100kD cell surface molecule expressed by cells of the myeloid lineage but not by T or B lymphocytes. This antibody has been shown to block the interaction of OX2 receptor 1 with CD200.
References
1. Wright, G.J. et al. (2000) Lymphoid/neuronal cell surface OX2 glycoprotein recognises a novel receptor on macrophages implicated in the control of their function. Immunity 13: 233-242. 2. Nathan, C. and Muller, W.A. (2001) Putting the brakes on innate immunity: a regulatory role for CD200. Nature Immunology 2: 17-19.|3. Dick, A.D. et al. (2001) Distribution of OX2 antigen and OX2 receptor within retina. IOVS 42: 170-176.