Reagenzien und Instrumente für die Immunologie Zellbiologie und Molekularbiologie
 
> CysOx2

CysOx2

Drucken Drucken
Melden Sie sich an

Katalog-Nummer HY-151505

Size : Getquote

Marke : MedChemExpress

Contact local distributor :


Telefonnummer : +1 850 650 7790

CysOx2 is a reaction-based fluorogenic probe for sulfenic acid (Ex/Em: 394/535 nm). CysOx2 can be used for detecting protein cysteine oxidation in living cells.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CysOx2 Chemische Struktur

CysOx2 Chemische Struktur

This product is a controlled substance and not for sale in your territory.

Beschreibung

CysOx2 is a reaction-based fluorogenic probe for sulfenic acid (Ex/Em: 394/535 nm). CysOx2 can be used for detecting protein cysteine oxidation in living cells[1].

IC50 & Target

Sulfenic acid[1]
In Vitro

CysOx2 (1 mM; 1 h) reacts with H2O2 and produces fluorescence in 50 mM HEPES pH 7.4[1].
CysOx2 is cell permeable[1].
CysOx2 (50 μM; 1 h) shows fluorescence signal in epitope-tagged wild-type EGFR expression HeLa cells, the signal is absent in C797S EGFR expression HeLa cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CysOx2 Related Antibodies
Molekulargewicht

305.32

Formel

C15H12FNO3S
SMILES

O=C1CS(=O)(C2=CC(F)=C(C3=CC=CC1=C32)N4CCC4)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise

  • [1]. Ferreira RB, et al. Reaction-based fluorogenic probes for detecting protein cysteine oxidation in living cells. Nat Commun. 2022 Sep 21;13(1):5522.  [Content Brief]

  • [1]. Ferreira RB, et al. Reaction-based fluorogenic probes for detecting protein cysteine oxidation in living cells. Nat Commun. 2022 Sep 21;13(1):5522.

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

CysOx2 Related Classifications

  • Others
  • Fluorescent Dye

  • Molaritätsrechner

  • Verdünnungsrechner

Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)

Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CysOx2CysOx 2CysOx-2Fluorescent Dyesulfenic acidliving cellcysteine oxidationfluorogenic probeInhibitorinhibitorinhibit