Heat Shock Protein B7, Recombinant, Human )

Katalog-Nummer H1834-80D-50ug

Size : 50ug

Marke : US Biological

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H1834-80D Heat Shock Protein B7, Recombinant, Human (Heat Shock Protein beta-7, HSPB7, Cardiovascular Heat Shock Protein, cvHsp, DKFZp779D0968, FLJ32733, Heat Shock 27kDa Protein Family Member 7 (Cardiovascular))

Clone Type
Polyclonal
Grade
Highly Purified
Applications
WB
Accession #
NP_055239
Shipping Temp
Blue Ice
Storage Temp
-20°C

HSPB7 is a member of HSPB (Heat shock protein beta) family. The HSPB family is one of the more diverse families within the group of HSP families. Some members have chaperone-like activities and/or play a role in cytoskeletal stabilization. Some members also show a dynamic, stress-induced translocation to SC35 splicing speckles. HSPB7 constitutively localized to SC35 splicing speckles, driven by its N-terminus. Unlike HSPB1 and HSPB5, that chaperoned heat unfolded substrates and kept them folding competent, HSPB7 did not support refolding. Recombinant HSPB7 protein was expressed in E. coli.||Source: |Recombinant corresponding to aa1-170 of human HSPB7 6x His tagged expressed in E. coli.||AA Sequence:|MGSSHHHHHH SSGLVPRGSH MSHRTSSTFR AERSFHSSSS SSSSSTSSSA SRALPAQDPP MEKALSMFSD DFGSFMRPHS EPLAFPARPG GAGNIKTLGD AYEFAVDVRD FSPEDIIVTT SNNHIEVRAE KLAADGTVMN TFAHKCQLPE DVDPTSVTSA LREDGSLTIR ARRHPHTEHV |QQTFRTEIKI||Applications: |Suitable for use in Western Blot. Other applications not tested.||Recommended Dilution:|Optimal dilutions to be determined by the researcher.||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Applications
Source: Recombinant, E. coli|Purity: ~ 85% (SDS-PAGE). Purified by using conventional chromatography techniques.|Concentration: As reported|Form: Supplied as a liquid in 20mM Tris HCl, pH 8.0, 200mM NaCl, 2mM DTT, 50% glycerol.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Form
Supplied as a liquid in 20mM Tris HCl, pH 8.0, 200mM NaCl, 2mM DTT, 50% glycerol.
Purity
~ 85% (SDS-PAGE). Purified by using conventional chromatography techniques.
References
1. VOS MJ., et al. (2009) Biochim Biophys Acta. 1793(8):1343-53. 2. Matkovich SJ, et al. (2010) J Clin Invest. 120(1):280-9