IL10 recombinant monoclonal antibody, clone 9D7
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- Specifications
Product Description
Rat recombinant monoclonal antibody raised against human IL10.
Antibody Species
Rat
Immunogen
Original antibody is raised against synthetic oligopeptide (containing an N-terminal cysteine)-carrier protein conjugates.
Reactivity
Human
Form
Liquid
Isotype
IgG1 kappa
Recommend Usage
Crystallography
ELISA
Immunofluorescence
Immunohistochemistry
Immunoprecipitation
Neutralization
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% Proclin 300)
Storage Instruction
Store at 4°C for 3 months. For long term storage, aliquot and store at -20°C.
Aliquot to avoid repeated freezing and thawing. - Applications
Immunohistochemistry
Immunofluorescence
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
Neutralization
Crystallography
- Gene Info — IL10
Entrez GeneID
3586Gene Name
IL10
Gene Alias
CSIF, IL-10, IL10A, MGC126450, MGC126451, TGIF
Gene Description
interleukin 10
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq
Other Designations
cytokine synthesis inhibitory factor
- Interactomes
- Pathways
- Diseases