Mouse ACACa (Acetyl Coenzyme A Carboxylase Alpha) Sandwich ELISA Kit

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	Acaca
Gene ID:	107476
Uniprot ID:	ACACA_MOUSE
Sample Type:	tissue homogenates, cell lysates or other biological fluids.

Tissue Specificity
Post Translational Modifications	Phosphorylation on Ser-1262 is required for interaction with BRCA1. Phosphorylation at Ser-79 by AMPK inactivates enzyme activity. The biotin cofactor is covalently attached to the central biotinyl-binding domain and is required for the catalytic activity.
Function	Cytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis. This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA.
Protein Name	Acetyl-Coa Carboxylase 1 Acc1 Acc-Alpha Acetyl-Coa Carboxylase 265
Database Links	Reactome: R-MMU-163765 Reactome: -MMU-196780 Reactome: -MMU-200425 Reactome: -MMU-75105
Cellular Localisation	Cytoplasm Cytosol
Alternative ELISA Names	Acetyl-Coa Carboxylase 1 ELISA kit Acc1 ELISA kit Acc-Alpha ELISA kit Acetyl-Coa Carboxylase 265 ELISA kit Acaca ELISA kit Acac ELISA kit Gm738 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance